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RNAi technology targeting the FGFR3-TACC3 fusion breakpoint: an opportunity for precision medicine
BACKGROUND: Fusion genes form as a result of abnormal chromosomal rearrangements linking previously separate genes into one transcript. The FGFR3-TACC3 fusion gene (F3-T3) has been shown to drive gliomagenesis in glioblastoma (GBM), a cancer that is notoriously resistant to therapy. However, success...
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| 出版年: | Neurooncol Adv |
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| 主要な著者: | , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7680176/ https://ncbi.nlm.nih.gov/pubmed/33241214 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/noajnl/vdaa132 |
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