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FGFR3-TACC3 is an oncogenic fusion protein in respiratory epithelium
Structural rearrangements of the genome can drive lung tumorigenesis through the generation of fusion genes with oncogenic properties. Advanced genomic approaches have identified the presence of a genetic fusion between fibroblast growth factor receptor 3 (FGFR3) and transforming acidic coiled-coil...
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| 發表在: | Oncogene |
|---|---|
| Main Authors: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2018
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6215478/ https://ncbi.nlm.nih.gov/pubmed/29991799 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-018-0399-5 |
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