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Influence of circular permutations on the structure and stability of a six‐fold circular symmetric designer protein

The β‐propeller fold is adopted by a sequentially diverse family of repeat proteins with apparent rotational symmetry. While the structure is mostly stabilized by hydrophobic interactions, an additional stabilization is provided by hydrogen bonds between the N‐and C‐termini, which are almost invaria...

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Detalhes bibliográficos
Publicado no:Protein Sci
Main Authors: Mylemans, Bram, Noguchi, Hiroki, Deridder, Els, Lescrinier, Eveline, Tame, Jeremy R. H., Voet, Arnout R. D.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7679965/
https://ncbi.nlm.nih.gov/pubmed/33006397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3961
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