Computational design of a self-assembling symmetrical β-propeller protein

The modular structure of many protein families, such as β-propeller proteins, strongly implies that duplication played an important role in their evolution, leading to highly symmetrical intermediate forms. Previous attempts to create perfectly symmetrical propeller proteins have failed, however. We...

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Bibliografiska uppgifter
Huvudupphovsmän: Voet, Arnout R. D., Noguchi, Hiroki, Addy, Christine, Simoncini, David, Terada, Daiki, Unzai, Satoru, Park, Sam-Yong, Zhang, Kam Y. J., Tame, Jeremy R. H.
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2014
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4210308/
https://ncbi.nlm.nih.gov/pubmed/25288768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1412768111
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