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Computational design of a self-assembling symmetrical β-propeller protein

The modular structure of many protein families, such as β-propeller proteins, strongly implies that duplication played an important role in their evolution, leading to highly symmetrical intermediate forms. Previous attempts to create perfectly symmetrical propeller proteins have failed, however. We...

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Main Authors: Voet, Arnout R. D., Noguchi, Hiroki, Addy, Christine, Simoncini, David, Terada, Daiki, Unzai, Satoru, Park, Sam-Yong, Zhang, Kam Y. J., Tame, Jeremy R. H.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4210308/
https://ncbi.nlm.nih.gov/pubmed/25288768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1412768111
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