Computational design of a self-assembling symmetrical β-propeller protein

The modular structure of many protein families, such as β-propeller proteins, strongly implies that duplication played an important role in their evolution, leading to highly symmetrical intermediate forms. Previous attempts to create perfectly symmetrical propeller proteins have failed, however. We...

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Autori principali: Voet, Arnout R. D., Noguchi, Hiroki, Addy, Christine, Simoncini, David, Terada, Daiki, Unzai, Satoru, Park, Sam-Yong, Zhang, Kam Y. J., Tame, Jeremy R. H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2014
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4210308/
https://ncbi.nlm.nih.gov/pubmed/25288768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1412768111
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