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Communication between RNA folding domains revealed by folding of circularly permuted ribozymes
To study the role of sequence and topology in RNA folding, we determined the kinetic folding pathways of two circularly permuted variants of the Tetrahymena group I ribozyme, using time-resolved hydroxyl radical footprinting. Circular permutation changes the distance between interacting residues in...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2007
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2175375/ https://ncbi.nlm.nih.gov/pubmed/17765924 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.07.007 |
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