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Influence of circular permutations on the structure and stability of a six‐fold circular symmetric designer protein

The β‐propeller fold is adopted by a sequentially diverse family of repeat proteins with apparent rotational symmetry. While the structure is mostly stabilized by hydrophobic interactions, an additional stabilization is provided by hydrogen bonds between the N‐and C‐termini, which are almost invaria...

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Bibliografiske detaljer
Udgivet i:Protein Sci
Main Authors: Mylemans, Bram, Noguchi, Hiroki, Deridder, Els, Lescrinier, Eveline, Tame, Jeremy R. H., Voet, Arnout R. D.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley & Sons, Inc. 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7679965/
https://ncbi.nlm.nih.gov/pubmed/33006397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3961
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