Mesenchyme-derived IGF2 is a major paracrine regulator of pancreatic growth and function

The genetic mechanisms that determine the size of the adult pancreas are poorly understood. Imprinted genes, which are expressed in a parent-of-origin-specific manner, are known to have important roles in development, growth and metabolism. However, our knowledge regarding their roles in the control...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Hammerle, Constanze M., Sandovici, Ionel, Brierley, Gemma V., Smith, Nicola M., Zimmer, Warren E., Zvetkova, Ilona, Prosser, Haydn M., Sekita, Yoichi, Lam, Brian Y. H., Ma, Marcella, Cooper, Wendy N., Vidal-Puig, Antonio, Ozanne, Susan E., Medina-Gómez, Gema, Constância, Miguel
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7678979/
https://ncbi.nlm.nih.gov/pubmed/33057429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1009069
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