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Differential genomic imprinting regulates paracrine and autocrine roles of IGF2 in mouse adult neurogenesis
Genomic imprinting is implicated in the control of gene dosage in neurogenic niches. Here we address the importance of Igf2 imprinting for murine adult neurogenesis in the subventricular zone (SVZ) and in the subgranular zone (SGZ) of the hippocampus in vivo. In the SVZ, paracrine IGF2 is a cerebros...
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| Publicado no: | Nat Commun |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Pub. Group
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4579569/ https://ncbi.nlm.nih.gov/pubmed/26369386 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9265 |
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