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Igf2 pathway dependency of the Trp53 developmental and tumour phenotypes

Insulin-like growth factor 2 (IGF2) and the transformation related protein 53 (Trp53) are potent regulators of cell growth and metabolism in development and cancer. In vitro evidence suggests several mechanistic pathway interactions. Here, we tested whether loss of function of p53 leads to IGF2 liga...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Haley, Victoria L, Barnes, David J, Sandovici, Ionel, Constancia, Miguel, Graham, Christopher F, Pezzella, Francesco, Bühnemann, Claudia, Carter, Emma J, Hassan, A Bassim
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: WILEY-VCH Verlag 2012
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3494071/
https://ncbi.nlm.nih.gov/pubmed/22674894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201101105
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