Igf2 pathway dependency of the Trp53 developmental and tumour phenotypes

Insulin-like growth factor 2 (IGF2) and the transformation related protein 53 (Trp53) are potent regulators of cell growth and metabolism in development and cancer. In vitro evidence suggests several mechanistic pathway interactions. Here, we tested whether loss of function of p53 leads to IGF2 liga...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Haley, Victoria L, Barnes, David J, Sandovici, Ionel, Constancia, Miguel, Graham, Christopher F, Pezzella, Francesco, Bühnemann, Claudia, Carter, Emma J, Hassan, A Bassim
Format: Artigo
Langue:Inglês
Publié: WILEY-VCH Verlag 2012
Sujets:
Research Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3494071/
https://ncbi.nlm.nih.gov/pubmed/22674894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201101105
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