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Estrogen-induced epigenetic silencing of FTH1 and TFRC genes reduces liver cancer cell growth and survival

Estrogen (E2) regulates hundreds of genes involved in cell metabolism and disrupts iron homoeostasis in various cell types. Herein, we addressed whether E2-induced epigenetic modifications are involved in modulating the expression of iron-regulatory genes. Epigenetic status of FTH1 and TFRC genes wa...

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Bibliographic Details
Published in:Epigenetics
Main Authors: Muhammad, Jibran Sualeh, Bajbouj, Khuloud, Shafarin, Jasmin, Hamad, Mawieh
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7678938/
https://ncbi.nlm.nih.gov/pubmed/32476555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2020.1770917
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