Enhanced CAR-T activity against established tumors by polarizing human T cells to secrete interleukin-9

CAR-T cell therapy is effective for hematologic malignancies. However, considerable numbers of patients relapse after the treatment, partially due to poor expansion and limited persistence of CAR-T cells in vivo. Here, we demonstrate that human CAR-T cells polarized and expanded under a Th9-culture...

全面介紹

Na minha lista:
書目詳細資料
發表在:Nat Commun
Main Authors: Liu, Lintao, Bi, Enguang, Ma, Xingzhe, Xiong, Wei, Qian, Jianfei, Ye, Lingqun, Su, Pan, Wang, Qiang, Xiao, Liuling, Yang, Maojie, Lu, Yong, Yi, Qing
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2020
主題:
Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7677397/
https://ncbi.nlm.nih.gov/pubmed/33214555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-19672-2
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!

相似書籍