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Enhanced lipid accumulation and metabolism are required for the differentiation and activation of tumor-associated macrophages
Tumor-associated macrophages (TAMs) are important tumor-promoting cells. However, the mechanisms underlying how the tumor and its microenvironment reprogram these cells remain elusive. Here we report that lipids play a crucial role in generating TAMs in the tumor microenvironment. Macrophages from b...
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| Pubblicato in: | Cancer Res |
|---|---|
| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7127942/ https://ncbi.nlm.nih.gov/pubmed/32015091 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-19-2994 |
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