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Mutant p53 in Cancer Progression and Targeted Therapies
TP53 is the most frequently mutated tumor suppressor gene in human cancer. The majority of mutations of p53 are missense mutations, leading to the expression of the full length p53 mutant proteins. Mutant p53 (Mutp53) proteins not only lose wild-type p53-dependent tumor suppressive functions, but al...
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| Udgivet i: | Front Oncol |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Frontiers Media S.A.
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7677253/ https://ncbi.nlm.nih.gov/pubmed/33240819 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.595187 |
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