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Discovery of Drugs Targeting Mutant p53 and Progress in Nano-Enabled Therapeutic Strategy for p53-Mutated Cancers

Mutations in the p53 gene are frequently observed in various cancers, prompting the initiation of efforts to restore p53 function as a therapeutic approach several decades ago. Nevertheless, only a limited number of drug development initiatives have progressed to late-stage clinical trials, and to d...

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Principais autores: Na Zhang, Zhiyuan Jing, Jie Song, Qiyue Liang, Yuxue Xu, Zhaowei Xu, Longping Wen, Pengfei Wei
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2025-05-01
coleção:Biomolecules
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Acesso em linha:https://www.mdpi.com/2218-273X/15/6/763
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