Single-cell lineage mapping of a diverse virus-specific naive CD4 T cell repertoire

Tracking how individual naive T cells from a natural TCR repertoire clonally expand, differentiate, and make lineage choices in response to an infection has not previously been possible. Here, using single-cell sequencing technology to identify clones by their unique TCR sequences, we were able to t...

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Библиографические подробности
Опубликовано в: :J Exp Med
Главные авторы: Khatun, Achia, Kasmani, Moujtaba Y., Zander, Ryan, Schauder, David M., Snook, Jeremy P., Shen, Jian, Wu, Xiaopeng, Burns, Robert, Chen, Yi-Guang, Lin, Chien-Wei, Williams, Matthew A., Cui, Weiguo
Формат: Artigo
Язык:Inglês
Опубликовано: Rockefeller University Press 2020
Предметы:
Brief Definitive Report
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7676493/
https://ncbi.nlm.nih.gov/pubmed/33201171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20200650
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