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E2A-regulated epigenetic landscape promotes memory CD8 T cell differentiation

During an acute viral infection, CD8 T cells encounter a myriad of antigenic and inflammatory signals of variable strength, which sets off individual T cells on their own differentiation trajectories. However, the developmental path for each of these cells will ultimately lead to one of only two pot...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Schauder, David M., Shen, Jian, Chen, Yao, Kasmani, Moujtaba Y., Kudek, Matthew R., Burns, Robert, Cui, Weiguo
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8072256/
https://ncbi.nlm.nih.gov/pubmed/33859041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2013452118
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