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Effect of pH on the Ability of N-Terminal Domain of Human NPC1 to Recognize, Bind, and Transfer Cholesterol
[Image: see text] Niemann–Pick type C1 (NPC1) is a large multidomain transmembrane protein essential for transporting cholesterol (CLR) from late endosomes and lysosomes to the endoplasmic reticulum and other cellular compartments. The lumen-facing N-terminal domain (NTD), involved in direct binding...
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| Опубликовано в: : | ACS Omega |
|---|---|
| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Chemical Society
2020
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| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7676335/ https://ncbi.nlm.nih.gov/pubmed/33225153 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.0c03983 |
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