Architecture of a SARS-CoV-2 mini replication and transcription complex

Non-structural proteins (nsp) constitute the SARS-CoV-2 replication and transcription complex (RTC) to play a pivotal role in the virus life cycle. Here we determine the atomic structure of a SARS-CoV-2 mini RTC, assembled by viral RNA-dependent RNA polymerase (RdRp, nsp12) with a template-primer RN...

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Publicat a:Nat Commun
Autors principals: Yan, Liming, Zhang, Ying, Ge, Ji, Zheng, Litao, Gao, Yan, Wang, Tao, Jia, Zhihui, Wang, Haofeng, Huang, Yucen, Li, Mingyu, Wang, Quan, Rao, Zihe, Lou, Zhiyong
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7675986/
https://ncbi.nlm.nih.gov/pubmed/33208736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-19770-1
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