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Beyond the Mevalonate Pathway: Control of Post-Prenylation Processing by Mutant p53

Missense mutations in the TP53 gene are among the most frequent alterations in human cancer. Consequently, many tumors show high expression of p53 point mutants, which may acquire novel activities that contribute to develop aggressive tumors. An unexpected aspect of mutant p53 function was uncovered...

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Bibliografiske detaljer
Udgivet i:Front Oncol
Main Authors: Borini Etichetti, Carla M, Arel Zalazar, Evelyn, Cocordano, Nabila, Girardini, Javier
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7674641/
https://ncbi.nlm.nih.gov/pubmed/33224889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.595034
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