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Beyond the Mevalonate Pathway: Control of Post-Prenylation Processing by Mutant p53

Missense mutations in the TP53 gene are among the most frequent alterations in human cancer. Consequently, many tumors show high expression of p53 point mutants, which may acquire novel activities that contribute to develop aggressive tumors. An unexpected aspect of mutant p53 function was uncovered...

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Publicat a:Front Oncol
Autors principals: Borini Etichetti, Carla M, Arel Zalazar, Evelyn, Cocordano, Nabila, Girardini, Javier
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7674641/
https://ncbi.nlm.nih.gov/pubmed/33224889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.595034
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