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Beyond the Mevalonate Pathway: Control of Post-Prenylation Processing by Mutant p53

Missense mutations in the TP53 gene are among the most frequent alterations in human cancer. Consequently, many tumors show high expression of p53 point mutants, which may acquire novel activities that contribute to develop aggressive tumors. An unexpected aspect of mutant p53 function was uncovered...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Borini Etichetti, Carla M, Arel Zalazar, Evelyn, Cocordano, Nabila, Girardini, Javier
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7674641/
https://ncbi.nlm.nih.gov/pubmed/33224889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.595034
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