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Beyond the Mevalonate Pathway: Control of Post-Prenylation Processing by Mutant p53
Missense mutations in the TP53 gene are among the most frequent alterations in human cancer. Consequently, many tumors show high expression of p53 point mutants, which may acquire novel activities that contribute to develop aggressive tumors. An unexpected aspect of mutant p53 function was uncovered...
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| Veröffentlicht in: | Front Oncol |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Frontiers Media S.A.
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7674641/ https://ncbi.nlm.nih.gov/pubmed/33224889 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.595034 |
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