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The Contrived Mutant p53 Oncogene – Beyond Loss of Functions

Mutations in p53 are almost synonymous with cancer – be it susceptibility to the disease or response to treatment – and therefore, are a critical determinant of overall survival. As most of these mutations occur in the DNA-binding domain of p53, many of the clinical correlations with mutant p53 have...

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Detaylı Bibliyografya
Yayımlandı:Front Oncol
Yazar: Sabapathy, Kanaga
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4674554/
https://ncbi.nlm.nih.gov/pubmed/26697411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2015.00276
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