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Understanding p53 functions through p53 antibodies

TP53 is the most frequently mutated gene across all cancer types. Our understanding of its functions has evolved since its discovery four decades ago. Initially thought to be an oncogene, it was later realized to be a critical tumour suppressor. A significant amount of our knowledge about p53 functi...

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Détails bibliographiques
Publié dans:J Mol Cell Biol
Auteurs principaux: Sabapathy, Kanaga, Lane, David P
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6487784/
https://ncbi.nlm.nih.gov/pubmed/30907951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jmcb/mjz010
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