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Current smoking with or without chronic bronchitis is independently associated with goblet cell hyperplasia in healthy smokers and COPD subjects

COPD, chronic bronchitis (CB) and active smoking have all been associated with goblet cell hyperplasia (GCH) in small studies. Active smoking is strongly associated with CB, but there is a disconnect between CB clinical symptoms and pathology. Chronic cough and sputum production poorly correlate wit...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kim, Victor, Jeong, Stephanie, Zhao, Huaqing, Kesimer, Mehmet, Boucher, Richard C., Wells, J. Michael, Christenson, Stephanie A., Han, MeiLan K., Dransfield, Mark, Paine, Robert, Cooper, Christopher B., Barjaktarevic, Igor, Bowler, Russell, Curtis, Jeffrey L., Kaner, Robert J., O’Beirne, Sarah L., O’Neal, Wanda K., Rennard, Stephen I., Martinez, Fernando J., Woodruff, Prescott G.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7674445/
https://ncbi.nlm.nih.gov/pubmed/33208859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-77229-1
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