Current smoking with or without chronic bronchitis is independently associated with goblet cell hyperplasia in healthy smokers and COPD subjects

COPD, chronic bronchitis (CB) and active smoking have all been associated with goblet cell hyperplasia (GCH) in small studies. Active smoking is strongly associated with CB, but there is a disconnect between CB clinical symptoms and pathology. Chronic cough and sputum production poorly correlate wit...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Kim, Victor, Jeong, Stephanie, Zhao, Huaqing, Kesimer, Mehmet, Boucher, Richard C., Wells, J. Michael, Christenson, Stephanie A., Han, MeiLan K., Dransfield, Mark, Paine, Robert, Cooper, Christopher B., Barjaktarevic, Igor, Bowler, Russell, Curtis, Jeffrey L., Kaner, Robert J., O’Beirne, Sarah L., O’Neal, Wanda K., Rennard, Stephen I., Martinez, Fernando J., Woodruff, Prescott G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7674445/
https://ncbi.nlm.nih.gov/pubmed/33208859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-77229-1
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