Elevated circulating MMP-9 is linked to increased COPD exacerbation risk in SPIROMICS and COPDGene

BACKGROUND. Matrix metalloprotease 9 (MMP-9) is associated with inflammation and lung remodeling in chronic obstructive pulmonary disease (COPD). We hypothesized that elevated circulating MMP-9 represents a potentially novel biomarker that identifies a subset of individuals with COPD with an inflamm...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:JCI Insight
मुख्य लेखकों: Wells, J. Michael, Parker, Margaret M., Oster, Robert A., Bowler, Russ P., Dransfield, Mark T., Bhatt, Surya P., Cho, Michael H., Kim, Victor, Curtis, Jeffrey L., Martinez, Fernando J., Paine, Robert, O’Neal, Wanda, Labaki, Wassim W., Kaner, Robert J., Barjaktarevic, Igor, Han, MeiLan K., Silverman, Edwin K., Crapo, James D., Barr, R. Graham, Woodruff, Prescott, Castaldi, Peter J., Gaggar, Amit, Investigators, the SPIROMICS and COPDGene
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Clinical Investigation 2018
विषय:
Research Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6302944/
https://ncbi.nlm.nih.gov/pubmed/30429371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.123614
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