The HIF1α/HIF2α-miR210-3p network regulates glioblastoma cell proliferation, dedifferentiation and chemoresistance through EGF under hypoxic conditions

Hypoxia-inducible factor 1α (HIF1α) promotes the malignant progression of glioblastoma under hypoxic conditions, leading to a poor prognosis for patients with glioblastoma; however, none of the therapies targeting HIF1α in glioblastoma have successfully eradicated the tumour. Therefore, we focused o...

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Veröffentlicht in:Cell Death Dis
Hauptverfasser: Wang, Pan, Yan, Qian, Liao, Bin, Zhao, Lu, Xiong, Shuanglong, Wang, Junwei, Zou, Dewei, Pan, Jinyu, Wu, Liangqi, Deng, Yangmin, Wu, Nan, Gong, Sheng
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7674439/
https://ncbi.nlm.nih.gov/pubmed/33208727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-03150-0
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