Methamphetamine induces cardiomyopathy by Sigmar1 inhibition-dependent impairment of mitochondrial dynamics and function

Methamphetamine-associated cardiomyopathy is the leading cause of death linked with illicit drug use. Here we show that Sigmar1 is a therapeutic target for methamphetamine-associated cardiomyopathy and defined the molecular mechanisms using autopsy samples of human hearts, and a mouse model of “bing...

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Xehetasun bibliografikoak
Argitaratua izan da:Commun Biol
Egile Nagusiak: Abdullah, Chowdhury S., Aishwarya, Richa, Alam, Shafiul, Morshed, Mahboob, Remex, Naznin Sultana, Nitu, Sadia, Kolluru, Gopi K., Traylor, James, Miriyala, Sumitra, Panchatcharam, Manikandan, Hartman, Brandon, King, Judy, Bhuiyan, Mohammad Alfrad Nobel, Chandran, Sunitha, Woolard, Matthew D., Yu, Xiuping, Goeders, Nicholas E., Dominic, Paari, Arnold, Connie L., Stokes, Karen, Kevil, Christopher G., Orr, A. Wayne, Bhuiyan, Md. Shenuarin
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2020
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7673131/
https://ncbi.nlm.nih.gov/pubmed/33203971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-020-01408-z
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