Doxorubicin-induced cardiomyopathy associated with inhibition of autophagic degradation process and defects in mitochondrial respiration

Doxorubicin (Dox) is a highly effective anticancer drug but cause acute ventricular dysfunction, and also induce late-onset cardiomyopathy and heart failure. Despite extensive studies, the pathogenic sequelae leading to the progression of Dox-associated cardiomyopathy remains unknown. We assessed te...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Abdullah, Chowdhury S., Alam, Shafiul, Aishwarya, Richa, Miriyala, Sumitra, Bhuiyan, Mohammad Alfrad Nobel, Panchatcharam, Manikandan, Pattillo, Christopher B., Orr, A. Wayne, Sadoshima, Junichi, Hill, Joseph A., Bhuiyan, Md. Shenuarin
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2019
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6376057/
https://ncbi.nlm.nih.gov/pubmed/30765730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-37862-3
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