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Synthetic rewiring and boosting type I interferon responses for visualization and counteracting viral infections
Mammalian first line of defense against viruses is accomplished by the interferon (IFN) system. Viruses have evolved numerous mechanisms to reduce the IFN action allowing them to invade the host and/or to establish latency. We generated an IFN responsive intracellular hub by integrating the syntheti...
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| 出版年: | Nucleic Acids Res |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2020
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7672444/ https://ncbi.nlm.nih.gov/pubmed/33137201 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa961 |
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