Myeloid Dendritic Cells Repress Human Cytomegalovirus Gene Expression and Spread by Releasing Interferon-Unrelated Soluble Antiviral Factors

Cytomegalovirus (CMV) is a betaherpesvirus that latently infects most adult humans worldwide and is a major cause of morbidity and mortality in immunocompromised hosts. Latent human CMV (HCMV) is believed to reside in precursors of myeloid-lineage leukocytes and monocytes, which give rise to macroph...

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Vydáno v:J Virol
Hlavní autoři: Kasmapour, Bahram, Kubsch, Tobias, Rand, Ulfert, Eiz-Vesper, Britta, Messerle, Martin, Vondran, Florian W. R., Wiegmann, Bettina, Haverich, Axel, Cicin-Sain, Luka
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2017
Témata:
Cellular Response to Infection
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5730771/
https://ncbi.nlm.nih.gov/pubmed/29046460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01138-17
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