Chromatin-Remodeling Factor SPOC1 Acts as a Cellular Restriction Factor against Human Cytomegalovirus by Repressing the Major Immediate Early Promoter

The cellular protein SPOC1 (survival time-associated PHD [plant homeodomain] finger protein in ovarian cancer 1) acts as a regulator of chromatin structure and the DNA damage response. It binds H3K4me2/3-containing chromatin and promotes DNA condensation by recruiting corepressors such as KAP-1 and...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Reichel, Anna, Stilp, Anne-Charlotte, Scherer, Myriam, Reuter, Nina, Lukassen, Sören, Kasmapour, Bahram, Schreiner, Sabrina, Cicin-Sain, Luka, Winterpacht, Andreas, Stamminger, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6026729/
https://ncbi.nlm.nih.gov/pubmed/29743358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00342-18
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