Uncoupling of the dynamics of host–pathogen interaction uncovers new mechanisms of viral interferon antagonism at the single-cell level

Antiviral defence in mammals is mediated through type-I interferons (IFNs). Viruses antagonise this process through expression of IFN antagonist proteins (IAPs). Understanding and modelling of viral escape mechanisms and the dynamics of IAP action has the potential to facilitate the development of s...

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Hlavní autoři: Rand, Ulfert, Hillebrand, Upneet, Sievers, Stephanie, Willenberg, Steffi, Köster, Mario, Hauser, Hansjörg, Wirth, Dagmar
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2014
Témata:
Methods Online
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4117750/
https://ncbi.nlm.nih.gov/pubmed/24895433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku492
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