Identification of a Predominantly Interferon-λ-Induced Transcriptional Profile in Murine Intestinal Epithelial Cells

Type I (α and β) and type III (λ) interferons (IFNs) induce the expression of a large set of antiviral effector molecules via their respective surface membrane receptors. Whereas most cell types respond to type I IFN, type III IFN preferentially acts on epithelial cells and protects mucosal organs s...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Selvakumar, Tharini A., Bhushal, Sudeep, Kalinke, Ulrich, Wirth, Dagmar, Hauser, Hansjörg, Köster, Mario, Hornef, Mathias W.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5650613/
https://ncbi.nlm.nih.gov/pubmed/29085367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01302
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