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CpG-ODN Facilitates Effective Intratracheal Immunization and Recall of Memory against Neoantigen-Expressing Alveolar Cells

Intrapulmonary immune reactions are impaired by the tolerogenic environment of the lung. This is manifested by the absence of effective endogenous T cell responses upon neoantigen expression. This tolerance is considered to contribute to lung cancer and inefficient immune therapeutic interventions....

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Detalles Bibliográficos
Publicado en:Front Immunol
Autores principales: Riehn, Mathias, Cebula, Marcin, Hauser, Hansjörg, Wirth, Dagmar
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5630691/
https://ncbi.nlm.nih.gov/pubmed/29038654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01201
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