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CpG-ODN Facilitates Effective Intratracheal Immunization and Recall of Memory against Neoantigen-Expressing Alveolar Cells

Intrapulmonary immune reactions are impaired by the tolerogenic environment of the lung. This is manifested by the absence of effective endogenous T cell responses upon neoantigen expression. This tolerance is considered to contribute to lung cancer and inefficient immune therapeutic interventions....

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Publicat a:Front Immunol
Autors principals: Riehn, Mathias, Cebula, Marcin, Hauser, Hansjörg, Wirth, Dagmar
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5630691/
https://ncbi.nlm.nih.gov/pubmed/29038654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01201
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