Reversible Silencing of Cytomegalovirus Genomes by Type I Interferon Governs Virus Latency

Herpesviruses establish a lifelong latent infection posing the risk for virus reactivation and disease. In cytomegalovirus infection, expression of the major immediate early (IE) genes is a critical checkpoint, driving the lytic replication cycle upon primary infection or reactivation from latency....

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Detalhes bibliográficos
Main Authors: Dağ, Franziska, Dölken, Lars, Holzki, Julia, Drabig, Anja, Weingärtner, Adrien, Schwerk, Johannes, Lienenklaus, Stefan, Conte, Ianina, Geffers, Robert, Davenport, Colin, Rand, Ulfert, Köster, Mario, Weiß, Siegfried, Adler, Barbara, Wirth, Dagmar, Messerle, Martin, Hauser, Hansjörg, Čičin-Šain, Luka
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3930589/
https://ncbi.nlm.nih.gov/pubmed/24586165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003962
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