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Combined ligand and structure-based virtual screening approaches for identification of novel AChE inhibitors

The excessive activity of acetylcholinesterase enzyme (AChE) causes different neuronal problems, especially dementia and neuronal cell deaths. Food and Drug Administration (FDA) approved drugs donepezil, rivastigmine, tacrine and galantamine are AChE inhibitors and in the treatment of Alzheimer’s di...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Turk J Chem
Hauptverfasser: ŞAHİN, Kader, DURDAĞI, Serdar
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Scientific and Technological Research Council of Turkey 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7671205/
https://ncbi.nlm.nih.gov/pubmed/33488178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3906/kim-1911-57
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