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Combined ligand and structure-based virtual screening approaches for identification of novel AChE inhibitors

The excessive activity of acetylcholinesterase enzyme (AChE) causes different neuronal problems, especially dementia and neuronal cell deaths. Food and Drug Administration (FDA) approved drugs donepezil, rivastigmine, tacrine and galantamine are AChE inhibitors and in the treatment of Alzheimer’s di...

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Bibliografski detalji
Izdano u:Turk J Chem
Glavni autori: ŞAHİN, Kader, DURDAĞI, Serdar
Format: Artigo
Jezik:Inglês
Izdano: The Scientific and Technological Research Council of Turkey 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7671205/
https://ncbi.nlm.nih.gov/pubmed/33488178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3906/kim-1911-57
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