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Structure-based and ligand-based virtual screening of novel methyltransferase inhibitors of the dengue virus

BACKGROUND: The dengue virus is the most significant arthropod-borne human pathogen, and an increasing number of cases have been reported over the last few decades. Currently neither vaccines nor drugs against the dengue virus are available. NS5 methyltransferase (MTase), which is located on the sur...

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Detalhes bibliográficos
Main Authors: Lim, See Ven, Rahman, Mohd Basyaruddin A, Tejo, Bimo A
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3278841/
https://ncbi.nlm.nih.gov/pubmed/22373153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-12-S13-S24
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