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Platycodin D enhances LDLR expression and LDL uptake via down-regulation of IDOL mRNA in hepatic cells

The root of Platycodon grandiflorum (PG) has long been used as a traditional herbal medicine in Asian country. Platycondin D (PD), triterpenoid saponin that is a main constituent of PG, exhibits various biological activities such as anti-inflammatory, anti-oxidant, anti-diabetic, and anti-cancer eff...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Choi, Yu-Jeong, Lee, Sol Ji, Kim, Hyo In, Lee, Hee Jung, Kang, So Jung, Kim, Tai Young, Cheon, Chunhoo, Ko, Seong-Gyu
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7670405/
https://ncbi.nlm.nih.gov/pubmed/33199761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-76224-w
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