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Feedback regulation of cholesterol uptake by the LXR-IDOL-LDLR axis
Inducible Degrader Of the Low-density lipoprotein receptor (IDOL) is an E3 ubiquitin ligase that mediates the ubiquitination and degradation of the low-density lipoprotein receptor (LDLR). IDOL expression is controlled at the transcriptional level by the cholesterol-sensing nuclear receptor LXR. In...
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| Pubblicato in: | Arterioscler Thromb Vasc Biol |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4280256/ https://ncbi.nlm.nih.gov/pubmed/22936343 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.112.250571 |
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