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Antimicrobial Synergy of a Ribonuclease and a Peptide Secreted by Human Cells
LL-37 is a secretory peptide that has antimicrobial activity. Ribonuclease 1 (RNase 1) is a secretory enzyme that is not cytotoxic. We find that human LL-37 and human RNase 1 can act synergistically to kill Gram-negative bacterial cells. In the presence of nontoxic concentrations of LL-37, RNase 1 i...
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| Udgivet i: | ACS Infect Dis |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7669604/ https://ncbi.nlm.nih.gov/pubmed/33054163 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.0c00594 |
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