Characterization of systemic genomic instability in budding yeast

Conventional models of genome evolution are centered around the principle that mutations form independently of each other and build up slowly over time. We characterized the occurrence of bursts of genome-wide loss-of-heterozygosity (LOH) in Saccharomyces cerevisiae, providing support for an additio...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Sampaio, Nadia M. V., Ajith, V. P., Watson, Ruth A., Heasley, Lydia R., Chakraborty, Parijat, Rodrigues-Prause, Aline, Malc, Ewa P., Mieczkowski, Piotr A., Nishant, Koodali T., Argueso, Juan Lucas
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2020
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7668020/
https://ncbi.nlm.nih.gov/pubmed/33106418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2010303117
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