Characterization of systemic genomic instability in budding yeast

Conventional models of genome evolution are centered around the principle that mutations form independently of each other and build up slowly over time. We characterized the occurrence of bursts of genome-wide loss-of-heterozygosity (LOH) in Saccharomyces cerevisiae, providing support for an additio...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Sampaio, Nadia M. V., Ajith, V. P., Watson, Ruth A., Heasley, Lydia R., Chakraborty, Parijat, Rodrigues-Prause, Aline, Malc, Ewa P., Mieczkowski, Piotr A., Nishant, Koodali T., Argueso, Juan Lucas
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7668020/
https://ncbi.nlm.nih.gov/pubmed/33106418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2010303117
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