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Karyotypic Determinants of Chromosome Instability in Aneuploid Budding Yeast
Recent studies in cancer cells and budding yeast demonstrated that aneuploidy, the state of having abnormal chromosome numbers, correlates with elevated chromosome instability (CIN), i.e. the propensity of gaining and losing chromosomes at a high frequency. Here we have investigated ploidy- and chro...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3355078/ https://ncbi.nlm.nih.gov/pubmed/22615582 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002719 |
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