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Environmental stresses induce karyotypic instability in colorectal cancer cells

Understanding how cells acquire genetic mutations is a fundamental biological question with implications for many different areas of biomedical research, ranging from tumor evolution to drug resistance. While karyotypic heterogeneity is a hallmark of cancer cells, few mutations causing chromosome in...

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Detalles Bibliográficos
Publicado en:Mol Biol Cell
Main Authors: Tan, Zhihao, Chan, Yong Jie Andrew, Chua, Ying Jie Karen, Rutledge, Samuel D., Pavelka, Norman, Cimini, Daniela, Rancati, Giulia
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Cell Biology 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6337910/
https://ncbi.nlm.nih.gov/pubmed/30379607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E18-10-0626
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