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Aneuploidy confers quantitative proteome changes and phenotypic variation in budding yeast

Aneuploidy, referring here to genome contents characterized by abnormal numbers of chromosomes, has been associated with developmental defects, cancer, and adaptive evolution in experimental organisms1–9. However, it remains unresolved how aneuploidy impacts gene expression and whether aneuploidy co...

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Autori principali: Pavelka, Norman, Rancati, Giulia, Zhu, Jin, Bradford, William D., Saraf, Anita, Florens, Laurence, Sanderson, Brian W., Hattem, Gaye L., Li, Rong
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2978756/
https://ncbi.nlm.nih.gov/pubmed/20962780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09529
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