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Aneuploidy confers quantitative proteome changes and phenotypic variation in budding yeast

Aneuploidy, referring here to genome contents characterized by abnormal numbers of chromosomes, has been associated with developmental defects, cancer, and adaptive evolution in experimental organisms1–9. However, it remains unresolved how aneuploidy impacts gene expression and whether aneuploidy co...

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Hlavní autoři: Pavelka, Norman, Rancati, Giulia, Zhu, Jin, Bradford, William D., Saraf, Anita, Florens, Laurence, Sanderson, Brian W., Hattem, Gaye L., Li, Rong
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2978756/
https://ncbi.nlm.nih.gov/pubmed/20962780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09529
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